Home Chemistry Organometallic Reagents Organoborons 2-([1,1'-Biphenyl]-4-Yl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
Suzuki-Miyaura Cross-Coupling: This reaction is one of the most common uses for boron compounds like 2-([1,1'-biphenyl]-4-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane. It involves the coupling of the boron compound with an aryl or vinyl halide or triflate in the presence of a palladium catalyst to form a new carbon-carbon bond. This is a powerful method for synthesizing biaryl compounds and other complex organic molecules.
Buchwald-Hartwig Amination: The boron compound can be used in Buchwald-Hartwig amination reactions to introduce amino groups into aryl or heteroaryl compounds. In this reaction, the boron compound reacts with an aryl halide and an amine in the presence of a palladium catalyst.
Sonogashira Coupling: This reaction involves coupling an aryl or vinyl boron compound with an aryl or vinyl halide in the presence of a palladium catalyst. It is used to form carbon-carbon triple bonds.
Hydrogenation: The boron compound can be hydrogenated to reduce the boron to a boron-free alkyl group, typically using a hydrogenation catalyst like palladium on carbon.
Borylation Reactions: The boron compound can be used in various borylation reactions to introduce boron atoms into organic molecules, which can then be further functionalized.
Reductive Elimination: In some cases, the boron compound can undergo reductive elimination reactions in the presence of suitable reagents, leading to the formation of new carbon-carbon or carbon-heteroatom bonds.
Oxidation Reactions: The boron compound can be oxidized to form boronic acids or boronate esters, which are important intermediates in various organic transformations.
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4'-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-[1,1'-biphenyl]-4-amine
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Methyl 4'-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-[1,1'-biphenyl]-3-carboxylate
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Methyl 4'-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-[1,1'-biphenyl]-4-carboxylate
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4'-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-[1,1'-biphenyl]-2-ol
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1-(4'-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-[1,1'-biphenyl]-4-yl)ethanone
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2-(3',5'-Difluoro-[1,1'-biphenyl]-4-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
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2-(4'-Isopropoxy-[1,1'-biphenyl]-4-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
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2-(4'-(Isopentyloxy)-[1,1'-biphenyl]-4-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
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4'-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-[1,1'-biphenyl]-4-carbonitrile
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